The Ghost Next Door is a 3D dynamic rogue-like which draws comparisons to Binding of Isaac, Rogue Legacy and Spelunky. Every floor is randomly generated, with different layouts of enemies, and features a boss at the end of each floor. It also features a nice flashlight mechanic, which is similar to (but better than) the mechanics used in Alan Wake.
You can download the Alpha from their Greenlight page, HERE
(click on the highlighted text that says ‘you can now try the alpha demo of the game’)